Dr Jacqueline Matthew January Seminar Series

December 17, 2025
We were pleased to welcome Dr Jacqueline Matthew - Clinical Research Fellow/Sonographer at King's College London - who delivered her talk “From Noise to Signal: A Clinical Researcher's Perspective on Translating Advances in Prenatal imaging into Practice" as part of our Seminar Series.

Abstract: Over the past decade, machine learning approaches in prenatal imaging has advanced from exploratory academic prototypes to clinically usable, real-time tools, but the path between those two endpoints is rarely straightforward. In this talk, Jacqueline offered a clinical researcher’s perspective on translating biomedical engineering innovations into real-world impact, tracing the journey from the iFIND project’s early breakthroughs in automated fetal imaging to the creation of Fraiya, an AI-driven ultrasound platform now entering clinical deployment. She unpacked the technical, clinical, and regulatory hurdles that shape this trajectory: data acquisition at scale, annotation complexity, model robustness, pipeline optimisation for real-time use, clinical safety engineering, regulatory strategy, and integration with NHS digital ecosystems. Beyond the technical achievements, the session reflected honestly on the innovation “gaps” that researchers and engineers encounter when stepping into entrepreneurship.  From productising research outputs, building 'with' clinicians and service users not just 'for' them, securing buy-in, navigating procurement, and proving value in operationally stretched healthcare services. The aim was to provide a pragmatic and motivating roadmap for researchers and innovators seeking to turn biomedical AI research into deployable, sustainable solutions in healthcare.

Seminar Series Event: “From Noise to Signal: A Clinical Researcher's Perspective on Translating Advances in Prenatal imaging into Practice.
Date and Time: Thursday 22 January 2026, 15:00 – 16.00 hrs (GMT)
Location: K39, King's Building, Strand Campus
Attendance: Mandatory for all DRIVE-Health students, therefore please accept the calendar invitation.
Registration: Alumni and wider King's College London research community all welcome - please email drive-health-cdt@kcl.ac.uk to let us know if you would like to attend.

Biography
Jacqueline is a clinical academic, sonographer, and MedTech entrepreneur with over 20 years of experience in advancing pregnancy care through compassionate, technology-driven solutions. Specialising in ultrasound and fetal MRI, Jacqueline’s work focuses on leveraging cutting-edge imaging technologies to improve screening, diagnosis, and care for pregnant women.
With a PhD in advanced 3D ultrasound and fetal MRI, Jacqueline uses machine learning to refine diagnostic pathways, pushing the boundaries of what’s possible in prenatal care. As Clinical Lead and Chief Medical Officer at an early-stage health tech startup, she has been at the forefront of developing a real-time AI-powered pregnancy ultrasound platform, with ambitions to transform how scans are performed, enhancing diagnostic accuracy, and empowering healthcare professionals to deliver more informed and compassionate care.

Jacqueline’s work has earned her widespread recognition, including being named one of the inaugural winners of the NHS England CAHPO Gold Award for Excellence, which celebrates health professionals who exemplify exceptional contributions to healthcare and the NHS values.

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March 12, 2026
We are looking forward to welcoming Professor Honghan Wu, Professor of Health Informatics and AI at the University of Glasgow, who will deliver his talk “Large language model and Radiology: how to facilitate human and AI collaboration? " as part of our Seminar Series. Abstract: In this upcoming talk, Professor Honghan Wu explores the essential shift from viewing AI as a potential replacement for radiologists to recognizing it as a critical collaborative partner. Moving beyond basic tasks like detection and triage, the presentation highlights how AI can address practical clinical "pain points," such as reducing automated protocoling time by up to 60% and decreasing the time spent communicating with providers and patients by 30%. Professor Wu will present recent research on using knowledge-retrieval and Large Language Models for clinical report error correction and generation. The session concludes with an examination of the real-world deployment lifecycle, discussing the challenges of monitoring the over 700 FDA-cleared radiology AI devices currently in practice Seminar Series Event : “Large language model and Radiology: how to facilitate human and AI collaboration?" Date and Time: Thursday 25 June 2026, 15:00 – 16.00 hrs (BST) Location: Large Committee Room, Hodgkin Building, Guy's Campus Attendance: Mandatory for all DRIVE-Health students; a calendar invitation has already been sent. Registration: Alumni and wider King's College London research community all welcome - please email drive-health-cdt@kcl.ac.uk to let us know if you would like to attend. Biography Honghan Wu is a Professor of Health Informatics and AI, based in the School of Health and Wellbeing of the University of Glasgow, where he leads the research theme of data science and AI. Prof Wu is a co-director of Health Data Research Scotland. He also is an honorary professor at Hong Kong University, an honorary associate professor at Institute of Health Informatics, UCL, and a former Turing Fellow of The Alan Turing Institute, UK's national institute for data science and artificial intelligence. Prof Wu holds a PhD in Computing Science. His current research focuses on machine learning, natural language processing, knowledge graph and their applications in medicine.
March 12, 2026
We are pleased to welcome Simon Ellershaw, PhD Candidate at University College London (UCL) as part of the UKRI UCL Centre for Doctoral Training in AI-enabled Healthcare Systems, who will deliver his talk “Developing Healthcare LLMs: From the NHS to Silicon Valley " as part of our Seminar Series. Abstract: This talk links my PhD and my Silicon Valley internship through one theme: what it really takes to build and deploy LLMs in healthcare. I will introduce Foresight England (Foresight E), a national-scale generative foundation model trained from scratch on 54.9 million de-identified longitudinal NHS EHRs to model patient timelines and enable zero-shot prediction across around 40,000 coded medical events. As NHS England has paused data access pending review, I will focus on the core methodology and lessons learned. I will then switch to my Parexel internship in San Francisco, where I worked in the company’s AI lab on production-focused applications, including pharmacovigilance and protocol de-risking. I will explain how I ended up there, what I worked on, and what I learned, with a candid view of what day-to-day life and work in the Bay Area actually looks like. I will also reflect on how the recent generative AI boom has reshaped the problems teams like ours choose to tackle and the way this work gets built, evaluated, and shipped. Seminar Series Event : “Developing Healthcare LLMs: From the NHS to Silicon Valley" Date and Time: Wednesday 27 May 2026, 15:00 – 16.00 hrs (BST) Location: Judy Dunn, SGDP Building, Denmark Hill Campus Attendance: Mandatory for all DRIVE-Health students; a calendar invitation has already been sent. Registration: Alumni and wider King's College London research community all welcome - please email drive-health-cdt@kcl.ac.uk to let us know if you would like to attend. Biography Simon Ellershaw is a PhD Candidate at University College London (UCL) as part of the UKRI UCL Centre for Doctoral Training in AI-enabled Healthcare Systems, supervised by Prof Richard Dobson and Dr Anoop Shah. His research spans LLM-based generation of hospital discharge summaries, national-scale pre-training of generative models on 57 million electronic health records, and post-training using real-world patient outcomes as verifiable reinforcement-learning rewards. Alongside his PhD, he interned at Parexel AI Labs and now works part-time as an NLP Engineer, developing and deploying production LLM/NLP systems, including applications in pharmacovigilance and quality assurance.