Available
Project number:
2025_45
Start date:
October 2025
Project themes:
Main supervisor:
Lecturer in Nutritional Sciences
Co-supervisor:
Professor Lucilla Poston
Additional Information:
Evaluating the Impact of Fortification of Non-Wholemeal Wheat Flour with Folic Acid on Maternal-Fetal and Child Outcomes in UK Mother-Child Cohorts
Background: In the UK, around 90% of women of childbearing age have insufficient folate levels, which heightens the risk of neural tube defects (NTDs) in early pregnancy. The UK has one of Europe's highest rates of NTDs, affecting 1,000 pregnancies annually. To address this, the UK Government will mandate folic acid fortification of non-wholemeal wheat flour starting in 2026, potentially reducing NTDs by 20%. Low maternal folate is also linked to health issues such as anemia in mothers and fetal growth problems.
Novelty & Importance: Countries with folic acid fortification have seen improved folate levels and lower NTD rates, but strategies differ in terms of folic acid doses and the food products chosen for fortification. To assess the impact of the folic acid fortification in the UK, researchers will use data from the MIREDA partnership, which tracks 70,000 pregnancies annually from diverse regions across England, Wales, and Scotland.
Aims & Objectives: The study aims to evaluate the effects of fortification on all maternal and infant health outcomes (incl. NTDs), examining trends in conditions like maternal anemia, miscarriage, and infant neurodevelopment. It will also investigate inequalities by geographical location and socio-demographic factors, such as ethnicity and obesity. Additionally, the study will assess cost-effectiveness and provide feedback to government organizations. The research will analyze changes in maternal folate levels before and after fortification and their association with health outcomes. The project will involve statistical analysis and offer opportunities for the PhD student to contribute to ongoing research and dissemination.
We are now accepting applications for 1 October 2025
How to apply
Candidates should possess or be expected to achieve a 1st or upper 2nd class degree in a relevant subject including the biosciences, computer science, mathematics, statistics, data science, chemistry, physics, and be enthusiastic about combining their expertise with other disciplines in the field of healthcare.
Important information for International Students:
It is the responsibility of the student to apply for their Student Visa. Please note that the EPSRC DRIVE-Health studentship does not cover the visa application fees or the Immigration Health Surcharge (IHS) required for access to the National Health Service. The IHS is mandatory for anyone entering the UK on a Student Visa and is currently £776 per year for each year of study. Further detail can be found under the International Students tab below.
Next Steps
- Applications submitted by the closing date of Thursday 6 February 2025 will be considered by the CDT. We will contact shortlisted applicants with information about this part of the recruitment process.
- Candidates will be invited to attend an interview. Interviews are projected to take place in April 2025.
- Project selection will be through a panel interview chaired by either Professor Richard Dobson and Professor Vasa Curcin (CDT Directors) followed by informal discussion with prospective supervisors.
- If you have any questions related to the specific project you are applying for, please contact the main supervisor of the project directly.
For any other questions about the recruitment process, please email us at